US20250082782A1

Transgene cassettes designed to express the human codon-optimized gene fmr1

University of Texas System

Abstract

This technology relates to polynucleotides comprising optimized FMR1 open reading frame (ORF) sequences, viral vectors comprising the same, and methods of using the same for delivery of the ORF to a cell or a subject and to treat disorders associated with aberrant expression of FMR1, such as …

University: University of Texas System
Assignee: The Board Of Regents Of The University Of Texas System
Inventor: Steven J. Gray
Priority date: January 28, 2022
Filing date: January 27, 2023
Publication date: March 13, 2025
Language: en
PDF source: https://patentimages.storage.googleapis.com/93/47/0d/afd937fecb6da2/US20250082782A1.pdf
Metadata fetched: August 29, 2026 00:35