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US20250109121A1

Potent and selective smarca2 degrading chimeric molecules as cancer …

University of Texas System

Abstract

Provided are heterobifunctional compounds for the treatment of SMARCA4 deficient cancers, which heterobifunctional compounds comprise a SMARCA2 binding moiety, a linker, and a ubiquitin ligase binding moiety.

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
Yonathan LISSANU
Priority date
December 28, 2021
Filing date
December 23, 2022
Publication date
April 03, 2025
Language
en
Metadata fetched
August 29, 2026 00:36