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US20250255905A1

Bcma chimeric antigen receptors and uses thereof

University of Texas System

Abstract

The present application provides BCMA targeting chimeric antigen receptor (CAR) comprising a BCMA binding region and an intracellular costimulatory domain derived from DAP10. Further provided are engineered immune effector cells (such as NK cells) comprising the chimeric antigen receptors.

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
Katy REZVANI
Priority date
April 18, 2023
Filing date
April 29, 2025
Publication date
August 14, 2025
Language
en
Metadata fetched
August 29, 2026 00:36