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US20250257361A1

Compositions and methods for treating liver diseases with sirnas targeting …

University of Texas Southwestern

Abstract

Disclosed herein are compositions comprising siRNAs capable of downregulating SET and MYND (Myeloid-Nervy-DEAF1) domain-containing protein 2 (SMYD2) gene expression or a variant thereof. Also disclosed herein are methods of using SMYD2 inhibitors in the treatment of a liver disease or injury, such …

University
University of Texas Southwestern
Assignee
The Board Of Regents Of The University Of Texas System
Inventor
Hao Zhu
Priority date
November 09, 2022
Filing date
October 06, 2023
Publication date
August 14, 2025
Language
en
Metadata fetched
August 28, 2026 19:16