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US20250283060A1

Compositions and methods relating to engineered rna polymerases with capping …

University of Texas System

Abstract

Disclosed herein is an engineered fusion enzyme composed of a prokaryotic phage RNA polymerase (T7 RNAP) and a viral capping enzyme (NP868R) for the generation of RNA transcripts containing a 5′ 7-methylguanylate cap.

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
Andrew Ellington
Priority date
April 25, 2022
Filing date
April 25, 2023
Publication date
September 11, 2025
Language
en
Metadata fetched
August 29, 2026 00:36