N,n'-diphenyl-4,4'-biphenyldicarboxamide analogs and their use in cancer …

Abstract

In one aspect, the disclosure relates to a for α-helix mimetics that can replicate the α-helices found at protein protein interaction (PPI) interfaces and can selectively discriminate cognate proteins in PPIs. In one aspect, the scaffolds have Formula I wherein each of X 1 -X 8 is individually …