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US20250362310A1

Structure-based probe for detection of transthyretin amyloid fibrils and …

University of Texas System

Abstract

Disclosures herein are directed to polypeptide probes that may be used to detect transthyretin (TTR) oligomers or fibrils in patient samples obtained from subjects with wildtype and mutant TTR alleles. Also provided are methods of using the provided probes to diagnose subjects with a TTR- …

University
University of Texas System
Assignee
The Board Of Regents Of The University Of Texas System
Inventor
Lorena SAELICES GOMEZ
Priority date
June 15, 2022
Filing date
June 14, 2023
Publication date
November 27, 2025
Language
en
Metadata fetched
August 29, 2026 00:35