US5498696A

Sterol regulatory element binding proteins and their use in screening assays

University of Texas Southwestern

Abstract

A nuclear protein which binds sterol regulatory elements (SREs), such as SRE-1 of the low density lipoprotein (LDL) receptor gene, and mediates sterol-regulated transcription of the LDL receptor gene is disclosed. Also described are screening assay and methods for the identification of agents …

University: University of Texas Southwestern
Assignee: Board Of Regents, The University Of Texas System
Inventor: Michael R. Briggs
Priority date: May 13, 1993
Filing date: May 13, 1993
Grant date: March 12, 1996
Publication date: March 12, 1996
Language: en
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