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US6395712B1

Sensitization of HER-2/neu overexpressing cancer cells to chemotherapy

University of Texas System

Abstract

The present invention relates to methods for the inhibition, of the gene product of the neu oncogene, p185neu tyrosine kinase. Over-expression of the neu oncogene leads to chemoresistance. The methods disclosed involve the novel use of E1A and/or LT in combination with chemotherapeutic drugs to …

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
Mien-Chie Hung
Priority date
March 20, 1996
Filing date
March 19, 1997
Grant date
May 28, 2002
Publication date
May 28, 2002
Language
en
Metadata fetched
August 28, 2026 23:57