US6528517B1

Synthesis of quinobenzoxazine analogues with topoisomerase II and quadruplex …

University of Texas System

Abstract

The present invention discloses a novel quinobenzoxazine self-assembly complex on DNA and on the topoisomerase II-DNA complex. The related model is used to design a new series of quinobenzoxazines, pyridobenzophenoxazines, pyrridonaphthophenoxazines, and other related compounds that may exhibit …

University: University of Texas System
Assignee: Board Of Regents, The University Of Texas System
Inventor: Laurence H. Hurley
Priority date: February 04, 1998
Filing date: February 04, 1999
Grant date: March 04, 2003
Publication date: March 04, 2003
Language: en
PDF source: https://patentimages.storage.googleapis.com/31/9a/5f/f67287d8c89af4/US6528517.pdf
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