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US6676941B2

Antibody conjugate formulations for selectively inhibiting VEGF

University of Texas System

Abstract

Disclosed are antibodies that specifically inhibit VEGF binding to only one (VEGFR2) of the two VEGF receptors. The antibodies effectively inhibit angiogenesis and induce tumor regression, and yet have improved safety due to their specificity. The present invention thus provides new antibody-based …

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
Philip E. Thorpe
Priority date
April 28, 1999
Filing date
November 30, 2001
Grant date
January 13, 2004
Publication date
January 13, 2004
Language
en
Metadata fetched
August 28, 2026 23:57