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US6703020B1

Antibody conjugate methods for selectively inhibiting VEGF

University of Texas System

Abstract

Disclosed are antibodies that specifically inhibit VEGF binding to only one (VEGFR2) of the two VEGF receptors. The antibodies effectively inhibit angiogenesis and induce tumor regression, and yet have improved safety due to their specificity. The present invention thus provides new antibody-based …

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
Philip E. Thorpe
Priority date
April 28, 1999
Filing date
April 28, 2000
Grant date
March 09, 2004
Publication date
March 09, 2004
Language
en
Metadata fetched
August 28, 2026 23:57