US6846957B2

Synthesis of 3-aminomethyl-1-propanol, a fluoxetine precursor

University of Texas System

Abstract

The present invention concerns a method of synthesizing fluoxetine hydrochloride. The method includes the synthesis of 3-methylamino-1-phenyl-1-propanol by reduction of 1-phenyl-3-methylamino-2-propen-1-one with sodium borohydride and acetic acid.

University: University of Texas System
Assignee: Board Of Regents, The University Of Texas System
Inventor: Alexander Zelenin
Priority date: November 22, 2002
Filing date: November 22, 2002
Grant date: January 25, 2005
Publication date: January 25, 2005
Language: en
PDF source: https://patentimages.storage.googleapis.com/d4/c3/37/5013ca798757a8/US6846957.pdf
Metadata fetched: August 28, 2026 23:58