US7144714B2

R2D2: an enzyme of RNA silencing

University of Texas System

Abstract

Methods for making siRNA comprise recombinantly coexpressing a Dicer protein with an R2D2 protein to form a complex comprising the R2D2 protein and the Dicer protein, and contacting the complex with a double-stranded (ds) RNA under conditions wherein the complex cleaves the dsRNA into siRNA. The …

University: University of Texas System
Assignee: Board Of Regents, The University Of Texas System
Inventor: Xiaodong Wang
Priority date: September 25, 2003
Filing date: September 25, 2003
Grant date: December 05, 2006
Publication date: December 05, 2006
Language: en
PDF source: https://patentimages.storage.googleapis.com/f7/1d/6e/9f2ee736c90a1a/US7144714.pdf
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