US7537903B2

FGF21 upregulates expression of GLUT-1 in a βklotho-dependent manner

University of Texas System

Abstract

A method is provided to identify a modulator of βKlotho-dependant glucose transporter-1 (GLUT-1) upregulation that specifically modulates interaction of βKlotho and an FGFR.

University: University of Texas System
Assignee: Board Of Regents, The University Of Texas System
Inventor: Makoto Kuro-o
Priority date: April 23, 2007
Filing date: April 23, 2008
Grant date: May 26, 2009
Publication date: May 26, 2009
Language: en
PDF source: https://patentimages.storage.googleapis.com/0a/b4/07/728f96a49a0336/US7537903.pdf
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