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US7622289B2

Ornithine aminotransferase (OAT): a target for anticancer drugs

University of Texas System

Abstract

Ornithine δ-aminotransferase (OAT) facilitates microtubule assembly in addition to its aminotransferase activity in mitochondria. An N-terminal proteolysis of the first 17 amino acids of OAT block its transport to the mitochondria. The resultant truncated protein (OATC) forms specific complexes …

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
Patrick Harran
Priority date
June 12, 2006
Filing date
June 12, 2006
Grant date
November 24, 2009
Publication date
November 24, 2009
Language
en
Metadata fetched
August 29, 2026 00:19