US7781413B2

SEMA3B inhibits tumor growth and induces apoptosis in cancer cells

University of Texas System

Abstract

The present invention identifies the semaphorin polypeptide SEMA3B as a tumor suppressor. This molecule can inhibit tumor growth and induce apoptosis of tumor cells when produced internally in a cancer cell via gene transfer, or when applied extracellularly. These observations permit new methods …

University: University of Texas System
Assignee: Board Of Regents, The University Of Texas System
Inventor: John Minna
Priority date: October 31, 2001
Filing date: October 31, 2002
Grant date: August 24, 2010
Publication date: August 24, 2010
Language: en
PDF source: https://patentimages.storage.googleapis.com/74/4e/a5/5fbb96604aa5fe/US7781413.pdf
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