US7858592B2

Interfering RNAs against the promoter region of P53

University of Texas System

Abstract

The present invention relates to the inhibition of p53 transcription by interfering with the activity of a p53 promoter using inhibitory double-stranded RNAs. Use of these inhibitory RNAs in the treatment of cancers also is disclosed.

University: University of Texas System
Assignee: The Board Of Regents Of The University Of Texas System
Inventor: David S. Shames
Priority date: February 26, 2007
Filing date: February 22, 2008
Grant date: December 28, 2010
Publication date: December 28, 2010
Language: en
PDF source: https://patentimages.storage.googleapis.com/2b/d4/2a/4ebfe50465c0d4/US7858592.pdf
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