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US8198252B2

SIRNA inhibition of PI3K P85, P110, and AKT2 and methods of use

University of Texas System

Abstract

The present invention provides polynucleotides, compositions including polynucleotides, and the uses thereof for treating cancer in a subject. The polynucleotides silence the expression of coding regions that encode polypeptides such as p85α, p110α, and Akt2. The cancers treatable using the …

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
B. Mark Evans
Priority date
May 19, 2006
Filing date
May 18, 2007
Grant date
June 12, 2012
Publication date
June 12, 2012
Language
en
Metadata fetched
August 29, 2026 00:20