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US8222221B2

Modulation of gene expression through endogenous small RNA targeting of gene …

University of Texas System

Abstract

Gene expression can be selectively regulated by endogenous miRNAs that target promoters of genes. Altering of the activity of these promoter-targeting miRNAs with single-stranded complementary oligonucleotides that bind the miRNA causes modulation of expression of the target gene. Endogenous …

University
University of Texas System
Assignee
The Board Of Regents Of The University Of Texas System
Inventor
David R. Corey
Priority date
June 04, 2008
Filing date
June 03, 2009
Grant date
July 17, 2012
Publication date
July 17, 2012
Language
en
Metadata fetched
August 29, 2026 00:20