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US8334239B2

High affinity VEGF-receptor antagonists

University of Texas System

Abstract

A cell-based screen is reported can be used to identify specific receptor-binding compounds in a combinatorial library of peptoids (N-alkylglycine oligomers) displayed on beads. This strategy was applied to the isolation of Vascular Endothelial Growth Factor Receptor 2 (VEGFR2)-binding peptoids, …

University
University of Texas System
Assignee
The Board Of Regents Of The University Of Texas System
Inventor
Thomas Kodadek
Priority date
July 10, 2007
Filing date
July 01, 2008
Grant date
December 18, 2012
Publication date
December 18, 2012
Language
en
Metadata fetched
August 29, 2026 00:20