US8394583B2

VH4 codon signature for multiple sclerosis

University of Texas Southwestern

Abstract

The present invention provides for the diagnosis and prediction of multiple sclerosis (MS) in subject utilizing a unique a codon signature in VH4 expressing B cells that has now been associated with MS and not with any other autoimmune disease.

University: University of Texas Southwestern
Assignee: The Board Of Regents Of The University Of Texas System
Inventor: Nancy Monson
Priority date: July 24, 2008
Filing date: July 24, 2009
Grant date: March 12, 2013
Publication date: March 12, 2013
Language: en
PDF source: https://patentimages.storage.googleapis.com/30/4f/54/0577be169b6507/US8394583.pdf
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