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US8614082B2

Attenuation of encephalitogenic alphavirus and uses thereof

University of Texas System

Abstract

The present invention is drawn to generating attenuated and less cytopathic forms of New World alphaviruses that can be used in immunogenic compositions as vaccines against both Old and New World alphaviruses. In this regard, the present invention discloses that the N-terminal, ˜35-aa-long …

University
University of Texas System
Assignee
The Board Of Regents Of The University Of Texas System
Inventor
Ilya V. Frolov
Priority date
August 16, 2007
Filing date
October 28, 2011
Grant date
December 24, 2013
Publication date
December 24, 2013
Language
en
Metadata fetched
August 29, 2026 00:21