US8658664B2

Cyclopamine tartrate salt and uses thereof

University of Texas System

Abstract

The present invention provides compositions and methods for modulating smoothened-dependent pathway activation. The present invention provides highly water-soluble analogs of cyclopamine that are potent, hedgehog signaling inhibitors less toxic than cyclopamine. The compounds of the present …

University: University of Texas System
Assignee: The Board Of Regents Of The University Of Texas System
Inventor: Jingwu Xie
Priority date: February 08, 2008
Filing date: August 09, 2010
Grant date: February 25, 2014
Publication date: February 25, 2014
Language: en
PDF source: https://patentimages.storage.googleapis.com/51/ea/e3/f19cc26300b674/US8658664.pdf
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