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US9233162B2

High affinity VEGF-receptor antagonists

University of Texas Southwestern

Abstract

A cell-based screen is reported can be used to identify specific receptor-binding compounds in a combinatorial library of peptoids (N-alkylglycine oligomers) displayed on beads. This strategy was applied to the isolation of Vascular Endothelial Growth Factor Receptor 2 (VEGFR2)-binding peptoids, …

University
University of Texas Southwestern
Assignee
The Board Of Regents Of The University Of Texas System
Inventor
Thomas Kodadek
Priority date
July 10, 2007
Filing date
November 19, 2010
Grant date
January 12, 2016
Publication date
January 12, 2016
Language
en
Metadata fetched
August 28, 2026 19:16