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US9375475B2

Combination immunotherapy for the treatment of cancer

University of Texas System

Abstract

Agonists to ICOS in combination with a blocking agent to a T cell inhibitory receptor (e.g., CTLA-4, PD-1, etc.) are demonstrated herein to be useful for the treatment of tumors.

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
James Allison
Priority date
September 30, 2009
Filing date
April 10, 2014
Grant date
June 28, 2016
Publication date
June 28, 2016
Language
en
Metadata fetched
August 29, 2026 00:23