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US9452182B2

Collateral gene inactivation biomarkers and targets for cancer therapy

University of Texas System

Abstract

Methods for treating a subject determined to have a cancer comprising a heterozygous inactivation of a housekeeping gene (or a homozygous deletion of a functionally redundant housekeeping gene) by treating the subject with an inhibitor of the gene. For example, a subject having a cancer with an …

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
Florian L. Muller
Priority date
December 14, 2011
Filing date
December 14, 2012
Grant date
September 27, 2016
Publication date
September 27, 2016
Language
en
Metadata fetched
August 29, 2026 00:23