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US9504658B2

Stabilized HME composition with small drug particles

University of Texas System

Abstract

A hot-melt extruded composition having finely divided drug-containing particles dispersed within a polymeric and/or lipophyllic carrier matrix is provided. The carrier softens or melts during hot-melt extrusion but it does not dissolve the drug-containing particles during extrusion. As a result, a …

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
Dave A. Miller
Priority date
November 09, 2004
Filing date
November 09, 2005
Grant date
November 29, 2016
Publication date
November 29, 2016
Language
en
Metadata fetched
August 29, 2026 00:24