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US9624484B2

Engineered primate L-methioninase for therapeutic purposes

University of Texas System

Abstract

Methods and compositions relating to the engineering of an improved protein with methionine-γ-lyase enzyme activity are described. For example, in certain aspects there may be disclosed a modified cystathionine-γ-lyase (CGL) comprising one or more amino acid substitutions and capable of degrading …

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
George Georgiou
Priority date
August 29, 2013
Filing date
October 18, 2016
Grant date
April 18, 2017
Publication date
April 18, 2017
Language
en
Metadata fetched
August 29, 2026 00:24