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US9732114B2

Compounds having anti-adhesive effects on cancer cells

University of Texas Southwestern

Abstract

Compounds of the form O-(x-L)n, where O is an oligonucleoside having at least a plurality of N3′→P5′ thiophosphoramidate (NPS) internucleoside linkages, a conjugated lipid moiety L, and at least one G-rich sequence motif as described, are effective to morphologically alter and reduce adhesion of …

University
University of Texas Southwestern
Assignee
Board Of Regents Of The University Of Texas System
Inventor
Sergei M. Gryaznov
Priority date
January 30, 2007
Filing date
July 21, 2014
Grant date
August 15, 2017
Publication date
August 15, 2017
Language
en
Metadata fetched
August 28, 2026 19:17